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Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
BACKGROUND: Osteoarthritis (OA) is the most common joint disease and is the leading cause of chronic disability among older people. Chondrocyte death and extracellular matrix (ECM) degradation was involved in OA pathogenesis. Ferroptosis was an iron-dependent cell death associated with peroxidation...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822178/ https://www.ncbi.nlm.nih.gov/pubmed/35101656 http://dx.doi.org/10.1016/j.ebiom.2022.103847 |