Continous, non-invasive monitoring of oxygen consumption in a parallelized microfluidic in vitro system provides novel insight into the response to nutrients and drugs of primary human hepatocytes

Oxygen plays a fundamental role in cellular energy metabolism, differentiation and cell biology in general. Consequently, in vitro oxygen sensing can be used to assess cell vitality and detect specific mechanisms of toxicity. In 2D in vitro models currently used, the oxygen supply provided by diffus...

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Detalles Bibliográficos
Autores principales: Busche, Marius, Rabl, Dominik, Fischer, Jan, Schmees, Christian, Mayr, Torsten, Gebhardt, Rolf, Stelzle, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822303/
https://www.ncbi.nlm.nih.gov/pubmed/35145369
http://dx.doi.org/10.17179/excli2021-4351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822303/
https://www.ncbi.nlm.nih.gov/pubmed/35145369
http://dx.doi.org/10.17179/excli2021-4351

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