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Multiomics Analysis of Structural Magnetic Resonance Imaging of the Brain and Cerebrospinal Fluid Metabolomics in Cognitively Normal and Impaired Adults

INTRODUCTION: Integrating brain imaging with large scale omics data may identify novel mechanisms of mild cognitive impairment (MCI) and early Alzheimer’s disease (AD). We integrated and analyzed brain magnetic resonance imaging (MRI) with cerebrospinal fluid (CSF) metabolomics to elucidate metaboli...

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Detalles Bibliográficos
Autores principales: Eldridge, Ronald C., Uppal, Karan, Shokouhi, Mahsa, Smith, M. Ryan, Hu, Xin, Qin, Zhaohui S., Jones, Dean P., Hajjar, Ihab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822333/
https://www.ncbi.nlm.nih.gov/pubmed/35145393
http://dx.doi.org/10.3389/fnagi.2021.796067