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Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages

The widespread coronavirus disease 2019 (COVID-19) is caused by infection with the novel coronavirus SARS-CoV-2. Currently, we have limited understanding of which cells become infected with SARS-CoV-2 in human tissues and where viral RNA localizes on the subcellular level. Here, we present a platfor...

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Detalles Bibliográficos
Autores principales: Acheampong, Kofi K., Schaff, Dylan L., Emert, Benjamin L., Lake, Jonathan, Reffsin, Sam, Shea, Emily K., Comar, Courtney E., Litzky, Leslie A., Khurram, Nigar A., Linn, Rebecca L., Feldman, Michael, Weiss, Susan R., Montone, Kathleen T., Cherry, Sara, Shaffer, Sydney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822351/
https://www.ncbi.nlm.nih.gov/pubmed/35130722
http://dx.doi.org/10.1128/mbio.03751-21