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Potentiating Vγ9Vδ2 T cell proliferation and assessing their cytotoxicity towards adherent cancer cells at the single cell level

Vγ9Vδ2 T cells is the dominant γδ T cell subset in human blood. They are cytotoxic and activated by phosphoantigens whose concentrations are increased in cancer cells, making the cancer cells targets for Vγ9Vδ2 T cell immunotherapy. For successful immunotherapy, it is important both to characterise...

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Detalles Bibliográficos
Autores principales: Liu, Chenxiao, Skorupinska-Tudek, Karolina, Eriksson, Sven-Göran, Parmryd, Ingela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822357/
https://www.ncbi.nlm.nih.gov/pubmed/34994391
http://dx.doi.org/10.1242/bio.059049