Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia

Transcriptome analyses performed in both human and zebrafish indicate strong expression of Apoe and Apoc1 by microglia. Apoe expression by microglia is well appreciated, but Apoc1 expression has not been well-examined. PPAR/RXR and LXR/RXR receptors appear to regulate expression of the apolipoprotei...

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Detalles Bibliográficos
Autores principales: Thiel, Whitney A., Esposito, Emma J., Findley, Anna P., Blume, Zachary I., Mitchell, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822359/
https://www.ncbi.nlm.nih.gov/pubmed/34878094
http://dx.doi.org/10.1242/bio.058990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822359/
https://www.ncbi.nlm.nih.gov/pubmed/34878094
http://dx.doi.org/10.1242/bio.058990

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