The c-Myc Oncogene Maintains Corneal Epithelial Architecture at Homeostasis, Modulates p63 Expression, and Enhances Proliferation During Tissue Repair

PURPOSE: The transcription factor c-Myc (Myc) plays central regulatory roles in both self-renewal and differentiation of progenitors of multiple cell lineages. Here, we address its function in corneal epithelium (CE) maintenance and repair. METHODS: Myc ablation in the limbal–corneal epithelium was...

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Detalles Bibliográficos
Autores principales: Portal, Céline, Wang, Zheng, Scott, Donald K., Wolosin, J. Mario, Iomini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822362/
https://www.ncbi.nlm.nih.gov/pubmed/35103750
http://dx.doi.org/10.1167/iovs.63.2.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822362/
https://www.ncbi.nlm.nih.gov/pubmed/35103750
http://dx.doi.org/10.1167/iovs.63.2.3

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