Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models

PURPOSE: To evaluate the effect of ATP-sensitive potassium channel openers cromakalim prodrug 1 (CKLP1) and diazoxide on IOP in three independent mouse models of ocular hypertension. METHODS: Baseline IOP was measured in TGFβ2 overexpression, steroid-induced, and iris dispersion (DBA/2J) ocular hype...

Descripción completa

Detalles Bibliográficos
Autores principales: Roy Chowdhury, Uttio, Millar, J. Cameron, Holman, Bradley H., Anderson, Kjersten J., Dosa, Peter I., Roddy, Gavin W., Fautsch, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822368/
https://www.ncbi.nlm.nih.gov/pubmed/35129587
http://dx.doi.org/10.1167/iovs.63.2.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822368/
https://www.ncbi.nlm.nih.gov/pubmed/35129587
http://dx.doi.org/10.1167/iovs.63.2.15

Ejemplares similares