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Synthesis and bioactivity of pyrrole-conjugated phosphopeptides

Here we report the synthesis and effect on the cell viability of pyrrole-conjugated phosphopeptides. Encouraged by the selective inhibition of cancer cells by a naphthyl-capped phosphopeptide (Nap-ff(p)y, 1), we conjugated the heteroaromatic dipyrrole or tripyrrole motif at the N-terminal of short p...

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Detalles Bibliográficos
Autores principales: Zhang, Qiuxin, Tan, Weiyi, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822458/
https://www.ncbi.nlm.nih.gov/pubmed/35186152
http://dx.doi.org/10.3762/bjoc.18.17