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Beware to ignore the rare: how imputing zero-values can improve the quality of 16S rRNA gene studies results
BACKGROUND: 16S rRNA-gene sequencing is a valuable approach to characterize the taxonomic content of the whole bacterial population inhabiting a metabolic and spatial niche, providing an important opportunity to study bacteria and their role in many health and environmental mechanisms. The analysis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822630/ https://www.ncbi.nlm.nih.gov/pubmed/35130833 http://dx.doi.org/10.1186/s12859-022-04587-0 |