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PD-L1 signaling in reactive astrocytes counteracts neuroinflammation and ameliorates neuronal damage after traumatic brain injury

BACKGROUND: Tissue damage and cellular destruction are the major events in traumatic brain injury (TBI), which trigger sterile neuroimmune and neuroinflammatory responses in the brain. While appropriate acute and transient neuroimmune and neuroinflammatory responses facilitate the repair and adaptat...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Li, Wei, Syed, Fahim, Yuan, Fang, Li, Ping, Yu, Qigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822654/
https://www.ncbi.nlm.nih.gov/pubmed/35135580
http://dx.doi.org/10.1186/s12974-022-02398-x