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Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair

BACKGROUND: Bone marrow-derived mesenchymal stem cells (MSCs), which possess immunomodulatory characteristic, are promising candidates for the treatment of acute myocardial infarction (AMI). However, the low retention and survival rate of MSCs in the ischemic heart limit their therapeutic efficacy....

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Detalles Bibliográficos
Autores principales: Xiong, Yuyan, Tang, Ruijie, Xu, Junyan, Jiang, Wenyang, Gong, Zhaoting, Zhang, Lili, Li, Xiaosong, Ning, Yu, Huang, Peisen, Xu, Jun, Chen, Guihao, Jin, Chen, Li, Xiangdong, Qian, Haiyan, Yang, Yuejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822662/
https://www.ncbi.nlm.nih.gov/pubmed/35130979
http://dx.doi.org/10.1186/s13287-022-02736-z