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Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair
BACKGROUND: Bone marrow-derived mesenchymal stem cells (MSCs), which possess immunomodulatory characteristic, are promising candidates for the treatment of acute myocardial infarction (AMI). However, the low retention and survival rate of MSCs in the ischemic heart limit their therapeutic efficacy....
Autores principales: | Xiong, Yuyan, Tang, Ruijie, Xu, Junyan, Jiang, Wenyang, Gong, Zhaoting, Zhang, Lili, Li, Xiaosong, Ning, Yu, Huang, Peisen, Xu, Jun, Chen, Guihao, Jin, Chen, Li, Xiangdong, Qian, Haiyan, Yang, Yuejin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822662/ https://www.ncbi.nlm.nih.gov/pubmed/35130979 http://dx.doi.org/10.1186/s13287-022-02736-z |
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