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CNS endothelial derived extracellular vesicles are biomarkers of active disease in multiple sclerosis

BACKGROUND: Multiple sclerosis (MS) is a complex, heterogenous disease characterized by inflammation, demyelination, and blood–brain barrier (BBB) permeability. Currently, active disease is determined by physician confirmed relapse or detection of contrast enhancing lesions via MRI indicative of BBB...

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Detalles Bibliográficos
Autores principales: Mazzucco, Michael, Mannheim, William, Shetty, Samantha V., Linden, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822708/
https://www.ncbi.nlm.nih.gov/pubmed/35135557
http://dx.doi.org/10.1186/s12987-021-00299-4