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Multidimensional analysis of the host response reveals prognostic and pathogen-driven immune subtypes among adults with sepsis in Uganda

BACKGROUND: The global burden of sepsis is concentrated in sub-Saharan Africa, where severe infections disproportionately affect young, HIV-infected adults and high-burden pathogens are unique. In this context, poor understanding of sepsis immunopathology represents a crucial barrier to development...

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Detalles Bibliográficos
Autores principales: Cummings, Matthew J., Bakamutumaho, Barnabas, Price, Adam, Owor, Nicholas, Kayiwa, John, Namulondo, Joyce, Byaruhanga, Timothy, Muwanga, Moses, Nsereko, Christopher, Sameroff, Stephen, Tokarz, Rafal, Wong, Wai, Shah, Shivang S., Larsen, Michelle H., Lipkin, W. Ian, Lutwama, Julius J., O’Donnell, Max R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822787/
https://www.ncbi.nlm.nih.gov/pubmed/35130948
http://dx.doi.org/10.1186/s13054-022-03907-3