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Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia–reperfusion injury are mediated by regulating the PI3K/AKT pathway

BACKGROUND: Neuroinflammation and apoptosis are involved in the pathogenesis of ischaemic stroke. Alisol A 24-acetate (24A) exerts a strong inhibitory effect on inflammation and cell apoptosis. The neuroprotective effect of 24A on global cerebral ischaemia/reperfusion (GCI/R) injury remains unclear....

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Detalles Bibliográficos
Autores principales: Lu, Taotao, Li, Huihong, Zhou, Yangjie, Wei, Wei, Ding, Linlin, Zhan, Zengtu, Liu, Weilin, Tao, Jing, Xue, Xiehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822821/
https://www.ncbi.nlm.nih.gov/pubmed/35130910
http://dx.doi.org/10.1186/s12974-022-02392-3