Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

BACKGROUND: The inflammation and oxidative stress (OS) have been considered crucial components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger, processes strong biological activities including antioxidant, anti-inflammatory and neuroprotective properties. However, its ro...

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Detalles Bibliográficos
Autores principales: Dang, Ruozhi, Wang, Mingyang, Li, Xinhui, Wang, Haiyang, Liu, Lanxiang, Wu, Qingyuan, Zhao, Jianting, Ji, Ping, Zhong, Lianmei, Licinio, Julio, Xie, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822843/
https://www.ncbi.nlm.nih.gov/pubmed/35130906
http://dx.doi.org/10.1186/s12974-022-02400-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822843/
https://www.ncbi.nlm.nih.gov/pubmed/35130906
http://dx.doi.org/10.1186/s12974-022-02400-6

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