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Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal stem cells (BMSC-exos) are extracellular vesicles that can execute the function of bone-marrow mesenchymal stem cells (B...

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Detalles Bibliográficos
Autores principales: Liu, Sen, Fan, Min, Xu, Jing-Xian, Yang, Long-Jun, Qi, Cong-Cong, Xia, Qing-Rong, Ge, Jin-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822863/
https://www.ncbi.nlm.nih.gov/pubmed/35130907
http://dx.doi.org/10.1186/s12974-022-02393-2