Cargando…

Overexpression of Foxc1 ameliorates sepsis-associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF-κB pathway

Sepsis-associated encephalopathy (SAE) is a common and severe complication of sepsis. The cognitive dysfunction that ensues during SAE has been reported to be caused by impairments of the hippocampus. Microglia serves a key role in neuroinflammation during SAE through migration. Forkhead box C1 (Fox...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hongyu, Wang, Hongwei, Song, Yinsen, Liu, Congyan, Qian, Xinling, Zhang, Dalong, Jiang, Xin, Zhang, Sisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822881/
https://www.ncbi.nlm.nih.gov/pubmed/35103290
http://dx.doi.org/10.3892/mmr.2022.12623