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4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis

OBJECTIVES/GOALS: Our lab previously identified a population of vascular smooth muscle (SMC)-derived progenitor cells (AdvSca1-SM) which expand robustly in response to disease and can differentiate into multiple cell types. We now aim to define the role of these AdvSca1-SM cells in atherosclerotic p...

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Detalles Bibliográficos
Autores principales: Dubner, Allison Milfred, Lu, Sizhao, Jolly, Austin, Strand, Keith, Mutryn, Marie, Tucker, Rebecca, Moulton, Karen, Nemenoff, Raphael A., Weiser-Evans, Mary C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822919/
http://dx.doi.org/10.1017/cts.2020.315