Cargando…
4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis
OBJECTIVES/GOALS: Our lab previously identified a population of vascular smooth muscle (SMC)-derived progenitor cells (AdvSca1-SM) which expand robustly in response to disease and can differentiate into multiple cell types. We now aim to define the role of these AdvSca1-SM cells in atherosclerotic p...
Autores principales: | Dubner, Allison Milfred, Lu, Sizhao, Jolly, Austin, Strand, Keith, Mutryn, Marie, Tucker, Rebecca, Moulton, Karen, Nemenoff, Raphael A., Weiser-Evans, Mary C.M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822919/ http://dx.doi.org/10.1017/cts.2020.315 |
Ejemplares similares
-
Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner
por: Dubner, Allison M, et al.
Publicado: (2023) -
Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis
por: Lu, Sizhao, et al.
Publicado: (2020) -
Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis
por: Jolly, Austin J., et al.
Publicado: (2023) -
3280 Mycobacterium bovis Bacille-Calmette-Guérin infection aggravates atherosclerosis
por: Huaman, Moises, et al.
Publicado: (2019) -
4119 Cholecystokinin (CCK) Receptor Antagonist Reverses Nonalcoholic Steatohepatitis (NASH) by Reducing Hepatic Macrophages and Inflammatory Cytokines
por: Gay, Martha, et al.
Publicado: (2020)