4346 Potential Sudden Unexpected Death in Epilepsy (SUDEP) Biomarkers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes with DEPDC5 Loss-of-Function

OBJECTIVES/GOALS: Sudden Unexpected Death in Epilepsy (SUDEP) is a leading cause of death in epilepsy patients. This study aims to determine whether cardiac mechanisms contribute to SUDEP in epilepsy patients with variants in DEPDC5, a gene encoding a member of the mTOR GATOR complex, to identify SU...

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Detalles Bibliográficos
Autores principales: Zhao, Yanting, Zhang, Helen, Parent, Jack M., Isom, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Mechanistic Basic to Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823003/
http://dx.doi.org/10.1017/cts.2020.311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823003/
http://dx.doi.org/10.1017/cts.2020.311

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