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4078 Identification of distinct fibroblast populations with unique roles in pancreatic cancer progression and tumor immunity

OBJECTIVES/GOALS: The desmoplastic reaction in PDAC involves a significant accumulation of immune cells and fibroblasts.The functional diversity of carcinoma associated fibroblasts (CAFs) remains largely unknown, and identification of immune regulating subsets would have a substantial impact in augm...

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Detalles Bibliográficos
Autores principales: Darpolor, Josephine Kebbeh, Zheng, Xiaofeng, Yang, Sujuan, Sugimoto, Hikaru, Carstens, Julienne, de Sampiao, Pedro Correa, LeBleu, Valerie, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823093/
http://dx.doi.org/10.1017/cts.2020.301