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Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE

OBJECTIVE: To examine the long-term changes in circulating B cell subsets and IgG levels at 5+ years of continuous belimumab treatment and their correlations with efficacy and safety measures. METHODS: This was a post hoc analysis of a continuation study (BEL112233; NCT00724867) of eligible US patie...

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Detalles Bibliográficos
Autores principales: Struemper, Herbert, Kurtinecz, Milena, Edwards, Lisa, Freimuth, William W, Roth, David A, Stohl, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823257/
https://www.ncbi.nlm.nih.gov/pubmed/35131846
http://dx.doi.org/10.1136/lupus-2021-000499