Chimeric Antigen Receptor T-Cell Therapy in Paediatric B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant?

Chimeric antigen receptor T-cell therapy (CAR-T) targeting CD19 has been associated with remarkable responses in paediatric patients and adolescents and young adults (AYA) with relapsed/refractory (R/R) B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). Tisagenlecleucel, the first approved CD...

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Detalles Bibliográficos
Autores principales: Buechner, Jochen, Caruana, Ignazio, Künkele, Annette, Rives, Susana, Vettenranta, Kim, Bader, Peter, Peters, Christina, Baruchel, André, Calkoen, Friso G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823293/
https://www.ncbi.nlm.nih.gov/pubmed/35145941
http://dx.doi.org/10.3389/fped.2021.784024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823293/
https://www.ncbi.nlm.nih.gov/pubmed/35145941
http://dx.doi.org/10.3389/fped.2021.784024

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