Cargando…

Chimeric Antigen Receptor T-Cell Therapy in Paediatric B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant?

Chimeric antigen receptor T-cell therapy (CAR-T) targeting CD19 has been associated with remarkable responses in paediatric patients and adolescents and young adults (AYA) with relapsed/refractory (R/R) B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). Tisagenlecleucel, the first approved CD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buechner, Jochen, Caruana, Ignazio, Künkele, Annette, Rives, Susana, Vettenranta, Kim, Bader, Peter, Peters, Christina, Baruchel, André, Calkoen, Friso G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823293/ https://www.ncbi.nlm.nih.gov/pubmed/35145941 http://dx.doi.org/10.3389/fped.2021.784024

Ejemplares similares

Blinatumomab as bridging therapy in paediatric B‐cell acute lymphoblastic leukaemia complicated by invasive fungal disease
por: Yeoh, Daniel K., et al.
Publicado: (2022)

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia
por: Da Costa, D, et al.
Publicado: (2013)

Subgrouping by gene expression profiles to improve relapse risk prediction in paediatric B‐precursor acute lymphoblastic leukaemia
por: Huang, Qingsheng, et al.
Publicado: (2021)

Role of apoptotic markers in paediatric acute lymphoblastic leukaemia
por: Kapoor, Gauri, et al.
Publicado: (2018)

Isolated Intraocular Relapse of Pediatric B-cell Precursor Acute Lymphoblastic Leukaemia Following Chimeric Antigen Receptor T-lymphocyte Therapy
por: Veys, Delphine, et al.
Publicado: (2020)

The choroid plexus stroma constitutes a sanctuary for paediatric B‐cell precursor acute lymphoblastic leukaemia in the central nervous system
por: Fernández‐Sevilla, Lidia M, et al.
Publicado: (2020)

Acute Lymphoblastic Leukaemia in the Youngest: Haematopoietic Stem Cell Transplantation and Beyond
por: Balduzzi, Adriana, et al.
Publicado: (2022)

Is asparaginase encapsulated in erythrocytes effective as second‐line treatment in acute lymphoblastic leukaemia?
por: van der Sluis, Inge M., et al.
Publicado: (2022)

Precursor B‐cell acute lymphoblastic leukaemia—a global view
por: Biondi, Andrea, et al.
Publicado: (2021)

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
por: Lilljebjörn, Henrik, et al.
Publicado: (2016)

Total Body Irradiation Forever? Optimising Chemotherapeutic Options for Irradiation-Free Conditioning for Paediatric Acute Lymphoblastic Leukaemia
por: Ben Hassine, Khalil, et al.
Publicado: (2021)

Minimal Residual Disease Prior to and After Haematopoietic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia: What Level of Negativity Is Relevant?
por: Merli, Pietro, et al.
Publicado: (2021)

Proteomics-based discovery of biomarkers for paediatric acute lymphoblastic leukaemia: challenges and opportunities
por: López Villar, Elena, et al.
Publicado: (2014)

Prediction of leukocyte counts during paediatric acute lymphoblastic leukaemia maintenance therapy
por: Karppinen, Santeri, et al.
Publicado: (2019)

The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy
por: Grobbelaar, Carle, et al.
Publicado: (2019)

Osteonecrosis in Korean Paediatric and Young Adults with Acute Lymphoblastic Leukaemia or Lymphoblastic Lymphoma: A Nationwide Epidemiological Study
por: Hahn, Seung Min, et al.
Publicado: (2022)

A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology
por: Hungate, Eric A., et al.
Publicado: (2016)

Brexucabtagene autoleucel for mantle cell lymphoma, B-cell precursor acute lymphoblastic leukaemia
Publicado: (2023)

Haematopoietic Stem Cell Transplantation in Adolescents and Young Adults With Acute Lymphoblastic Leukaemia: Special Considerations and Challenges
por: Calvo, Charlotte, et al.
Publicado: (2022)

Reversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression
por: Toscan, Cara E., et al.
Publicado: (2020)

Increasing completion of asparaginase treatment in childhood acute lymphoblastic leukaemia (ALL): summary of an expert panel discussion
por: Baruchel, André, et al.
Publicado: (2020)

Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity
por: Kutszegi, Nóra, et al.
Publicado: (2015)

Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions
por: Venn, Nicola C., et al.
Publicado: (2022)

Superior mediastinal syndrome in paediatric B-cell acute lymphoblastic leukaemia: a case report
por: Rahat-Ul-Ain,, et al.
Publicado: (2022)

The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
por: Chulián, Salvador, et al.
Publicado: (2023)

Childhood acute lymphoblastic leukaemia and indicators of early immune stimulation: the Estelle study (SFCE)
por: Ajrouche, R, et al.
Publicado: (2015)

Overweight and obesity management strategies in survivors of paediatric acute lymphoblastic leukaemia: a systematic review protocol
por: Ladhani, Salma, et al.
Publicado: (2018)

Paediatric pre‐B acute lymphoblastic leukaemia‐derived exosomes regulate immune function in human T cells
por: Gholipour, Elham, et al.
Publicado: (2022)

Impact of early chimerism status on clinical outcome in children with acute lymphoblastic leukaemia after haematopoietic stem cell transplantation
por: Lejman, Monika, et al.
Publicado: (2019)

French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
por: Trioche, Pascale, et al.
Publicado: (2012)

Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia
por: Forero-Castro, Maribel, et al.
Publicado: (2017)

A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites
Publicado: (1988)

T lymphoblastic leukaemia and the central nervous system.
por: Lilleyman, J. S., et al.
Publicado: (1981)

Long survival in childhood lymphoblastic leukaemia.
por: Chessells, J. M., et al.
Publicado: (1987)

Inotuzumab ozogamicin for acute lymphoblastic leukaemia
Publicado: (2019)

Targeted Therapy in Acute Lymphoblastic Leukaemia
por: Salvaris, Ross, et al.
Publicado: (2021)

Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia
por: Lu, Y, et al.
Publicado: (2014)

Low spontaneous apoptosis index at diagnosis predicts a high-risk phenotype in paediatric acute lymphoblastic leukaemia
por: Singh, Ankita, et al.
Publicado: (2018)

An information-theory analysis of DNA methylation identifies converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia
por: Koldobskiy, Michael A., et al.
Publicado: (2021)

Editorial: Allogeneic haematopoietic stem cell transplantation for children with acute lymphoblastic leukaemia in the era of immunotherapy
por: Peters, Christina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dtm08h6vhjo84fei6ujbs0lvbi