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4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes

OBJECTIVES/GOALS: Lupus lesional skin has elevated interferon expression, is highly colonized with Staphylococcus aureus (50%) and has no FDA-approved treatment options. We decided to investigate the effect of topical antibiotics on lupus lesional skin to determine whether it affects inflammatory ge...

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Detalles Bibliográficos
Autores principales: Sirobhushanam, Sirisha, Billi, Allison C, Berthier, Celine C, Tsoi, Lam C, Gudjonsson, Johann E, Kahlenberg, J Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823398/
http://dx.doi.org/10.1017/cts.2020.390