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4421 Exposure to topical antimicrobials reduces inflammatory gene expression in keratinocytes

OBJECTIVES/GOALS: Lupus lesional skin has elevated interferon expression, is highly colonized with Staphylococcus aureus (50%) and has no FDA-approved treatment options. We decided to investigate the effect of topical antibiotics on lupus lesional skin to determine whether it affects inflammatory ge...

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Detalles Bibliográficos
Autores principales:	Sirobhushanam, Sirisha, Billi, Allison C, Berthier, Celine C, Tsoi, Lam C, Gudjonsson, Johann E, Kahlenberg, J Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Translational Science, Policy, & Health Outcomes Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823398/ http://dx.doi.org/10.1017/cts.2020.390

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