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4096 Refined structure of human ferroportin using restraints from mass spectrometry

OBJECTIVES/GOALS: Mammals require iron for hemoglobin, respiration, immunity and as cofactor in enzymes. But free iron is toxic from the production of reactive oxygen species. Ferroportin is the sole exporter of cellular iron and it crucially determines cellular and systemic iron levels. Labile iron...

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Detalles Bibliográficos
Autores principales: Parry, Christian S., Ivanov, Andrey, Vazquez-meves, Guelaguetza, Alhakami, Fatemah A., Agyepong, Jessika, Han, Kyungreem, Brooks, Bernard R., Nekhai, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823464/
http://dx.doi.org/10.1017/cts.2020.314