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4535 Development of a Mouse Model to study interactions between parental history of alcohol use and early life adversity on behavioral and neurobiological development of offspring

OBJECTIVES/GOALS: Individuals with a family history of alcoholism (FH+) are more likely to develop an alcohol use disorder than those with no such history. Early life adversity has a high coincidence with FH+ making pathogenic studies difficult in clinical studies. Here, we developed a mouse model t...

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Detalles Bibliográficos
Autores principales: Porter, Grace, Morales, Juan, Valdespino, Roslyn, Acheson, Ashley, O’Connor, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823507/
http://dx.doi.org/10.1017/cts.2020.61