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4163 Aging and Smoking Exacerbates Post-Stroke Complement Driven Neuroinflammation

OBJECTIVES/GOALS: Following stroke, complement-dependent neuroinflammation exacerbates secondary injury and worsens acute and chronic outcomes. We have shown that an injury site-targeted complement inhibitor (B4Crry), that targets specifically to the ischemic brain, inhibits complement activation le...

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Detalles Bibliográficos
Autor principal: Couch, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823535/
http://dx.doi.org/10.1017/cts.2020.50