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4090 Dysregulation of Skeletal Muscle Mitochondrial Function following Critical Illness: a Translational Approach

OBJECTIVES/GOALS: The objective of the study was to determine whether CLP altered genes associated with mitochondrial function in the diaphragm. METHODS/STUDY POPULATION: A rodent cecal-ligation and puncture (CLP) model used to mimic sepsis-induced critical illness. The CLP model involved ligation o...

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Detalles Bibliográficos
Autores principales: Gill, Luther, Simon, Liz, Molina, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823613/
http://dx.doi.org/10.1017/cts.2020.296