Cooling intact and demembranated trabeculae from rat heart releases myosin motors from their inhibited conformation

Myosin filament–based regulation supplements actin filament–based regulation to control the strength and speed of contraction in heart muscle. In diastole, myosin motors form a folded helical array that inhibits actin interaction; during contraction, they are released from that array. A similar stru...

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Detalles Bibliográficos
Autores principales: Ovejero, Jesus G., Fusi, Luca, Park-Holohan, So-Jin, Ghisleni, Andrea, Narayanan, Theyencheri, Irving, Malcolm, Brunello, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823665/
https://www.ncbi.nlm.nih.gov/pubmed/35089319
http://dx.doi.org/10.1085/jgp.202113029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823665/
https://www.ncbi.nlm.nih.gov/pubmed/35089319
http://dx.doi.org/10.1085/jgp.202113029

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