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Cooling intact and demembranated trabeculae from rat heart releases myosin motors from their inhibited conformation
Myosin filament–based regulation supplements actin filament–based regulation to control the strength and speed of contraction in heart muscle. In diastole, myosin motors form a folded helical array that inhibits actin interaction; during contraction, they are released from that array. A similar stru...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823665/ https://www.ncbi.nlm.nih.gov/pubmed/35089319 http://dx.doi.org/10.1085/jgp.202113029 |