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Age-related differences in SARS-CoV-2 binding factors: An explanation for reduced susceptibility to severe COVID-19 among children?

CONTEXT: In contrast with other respiratory viruses, children infected with SARS-CoV-2 are largely spared from severe COVID-19. OBJECTIVES: To critically assess age-related differences in three host proteins involved in SARS-CoV-2 cellular entry: angiotensin-converting enzyme 2 (ACE2), transmembrane...

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Detalles Bibliográficos
Autores principales: Abrehart, Thomas, Suryadinata, Randy, McCafferty, Conor, Jacobson, Jonathan, Ignjatovic, Vera, Robinson, Phil, Crawford, Nigel W., Monagle, Paul, Subbarao, Kanta, Satzke, Catherine, Wurzel, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823960/
https://www.ncbi.nlm.nih.gov/pubmed/35227628
http://dx.doi.org/10.1016/j.prrv.2022.01.008