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In silico analysis of mutant epitopes in new SARS-CoV-2 lineages suggest global enhanced CD8+ T cell reactivity and also signs of immune response escape

SARS-CoV-2 variants of concern have emerged since the COVID-19 outburst, notably the lineages detected in the UK, South Africa, and Brazil. Their increased transmissibility and higher viral load put them in the spotlight. Much has been investigated on the ability of those new variants to evade antib...

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Detalles Bibliográficos
Autores principales: Pretti, Marco Antônio M., Galvani, Rômulo G., Scherer, Nicole M., Farias, Alessandro S., Boroni, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824006/
https://www.ncbi.nlm.nih.gov/pubmed/35149224
http://dx.doi.org/10.1016/j.meegid.2022.105236