CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA

HuR overexpression is related to poor survival in patients with colon cancer. HuR overexpression leads to stabilization of tumor-promoting mRNAs by binding to 3′UTR-resident AREs. Exosomes, nanosized lipid bilayer vesicles, mediate many steps in cancer progression. The potential role of exosomal HuR...

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Detalles Bibliográficos
Autores principales: Xiao, Hui, Ye, Xiong, Vishwakarma, Vikalp, Preet, Ranjan, Dixon, Dan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824215/
https://www.ncbi.nlm.nih.gov/pubmed/35130122
http://dx.doi.org/10.1080/15384047.2022.2034455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824215/
https://www.ncbi.nlm.nih.gov/pubmed/35130122
http://dx.doi.org/10.1080/15384047.2022.2034455

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