Cargando…

CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA

HuR overexpression is related to poor survival in patients with colon cancer. HuR overexpression leads to stabilization of tumor-promoting mRNAs by binding to 3′UTR-resident AREs. Exosomes, nanosized lipid bilayer vesicles, mediate many steps in cancer progression. The potential role of exosomal HuR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Hui, Ye, Xiong, Vishwakarma, Vikalp, Preet, Ranjan, Dixon, Dan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824215/ https://www.ncbi.nlm.nih.gov/pubmed/35130122 http://dx.doi.org/10.1080/15384047.2022.2034455

Ejemplares similares

Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
por: Yi, Jie, et al.
Publicado: (2010)

Regulation of HuR structure and function by dihydrotanshinone-I
por: Lal, Preet, et al.
Publicado: (2017)

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis
por: Blanco, Fernando F., et al.
Publicado: (2016)

Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines
por: Zhang, Xian, et al.
Publicado: (2009)

Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines
por: Zhang, Xian, et al.
Publicado: (2014)

AUF1 and HuR: possible implications of mRNA stability in thyroid function and disorders
por: Trojanowicz, Bogusz, et al.
Publicado: (2011)

Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation
por: Blackinton, Jeff G., et al.
Publicado: (2016)

Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA
por: Sundvold, Hilde
Publicado: (2020)

Correction to ‘Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines’
Publicado: (2023)

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
por: Kaur, Kawaljit, et al.
Publicado: (2017)

The lncRNA HMS recruits RNA-binding protein HuR to stabilize the 3′-UTR of HOXC10 mRNA
por: Priyanka, Priyanka, et al.
Publicado: (2021)

Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis
por: García-Domínguez, Daniel J., et al.
Publicado: (2011)

The formation of HuR/YB1 complex is required for the stabilization of target mRNA to promote myogenesis
por: Sánchez, Brenda Janice, et al.
Publicado: (2023)

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA
por: López de Silanes, Isabel, et al.
Publicado: (2009)

RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability
por: Cho, Seong Jun, et al.
Publicado: (2010)

Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
por: Mansfield, Kyle D., et al.
Publicado: (2012)

The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis
por: Ye, Xiong, et al.
Publicado: (2022)

HuR Promotes the Differentiation of Goat Skeletal Muscle Satellite Cells by Regulating Myomaker mRNA Stability
por: Sun, Yanjin, et al.
Publicado: (2023)

Destabilization of Nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fiber formation
por: Cammas, Anne, et al.
Publicado: (2014)

RNA-binding proteins La and HuR cooperatively modulate translation repression of PDCD4 mRNA
por: Kumar, Ravi, et al.
Publicado: (2020)

The RNA-Binding Protein HuR in Digestive System Tumors
por: Song, Xiaoqing, et al.
Publicado: (2020)

Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal
por: Liu, Lan, et al.
Publicado: (2015)

miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration
por: Zhuang, Ran, et al.
Publicado: (2013)

HuR stabilizes TFAM mRNA in an ATM/p38‐dependent manner in ionizing irradiated cancer cells
por: Zhang, Rui, et al.
Publicado: (2018)

Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization
por: Ke, Yueshuang, et al.
Publicado: (2020)

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
por: Kurosu, T, et al.
Publicado: (2011)

HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA
por: Dormoy-Raclet, Virginie, et al.
Publicado: (2013)

Synergistic regulation of Rgs4 mRNA by HuR and miR-26/RISC in neurons
por: Ehses, Janina, et al.
Publicado: (2020)

MCD Diet Modulates HuR and Oxidative Stress-Related HuR Targets in Rats
por: Ferrigno, Andrea, et al.
Publicado: (2023)

Different modes of interaction by TIAR and HuR with target RNA and DNA
por: Kim, Henry S., et al.
Publicado: (2011)

The RNA-binding protein HuR is a negative regulator in adipogenesis
por: Siang, Diana Teh Chee, et al.
Publicado: (2020)

Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
por: Chen, Jiaxin, et al.
Publicado: (2021)

LncRNA EBLN3P Facilitates Osteosarcoma Metastasis by Enhancing Annexin A3 mRNA Stability and Recruiting HuR
por: Wang, Shengtao, et al.
Publicado: (2023)

Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function
por: D’Agostino, Vito Giuseppe, et al.
Publicado: (2015)

HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner
por: Zhao, Quan, et al.
Publicado: (2020)

Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity
por: McCarthy, Grace A, et al.
Publicado: (2023)

Loss of RNA-binding protein HuR facilitates cellular senescence through posttranscriptional regulation of TIN2 mRNA
por: Lee, Ji Hoon, et al.
Publicado: (2018)

Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function
por: Yu, Ting-Xi, et al.
Publicado: (2011)

Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
por: Jimbo, Masaya, et al.
Publicado: (2015)

Cytoskeleton-Dependent Transport as a Potential Target for Interfering with Post-transcriptional HuR mRNA Regulons
por: Eberhardt, Wolfgang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_en3pjoit1s8l5gkd1fvtm0cadp