MERS-CoV nsp1 impairs the cellular metabolic processes by selectively downregulating mRNAs in a novel granules

MERS-CoV infection can damage the cellular metabolic processes, but the underlying mechanisms are largely unknown. Through screening, we found non-structural protein 1 (nsp1) of MERS-CoV could inhibit cell viability, cell cycle, and cell migration through its endonuclease activity. Transcriptome seq...

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Detalles Bibliográficos
Autores principales: Pan, Zhaoyi, Feng, Yujie, Wang, Zhihui, Lei, Zhengyang, Han, Qiuju, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824216/
https://www.ncbi.nlm.nih.gov/pubmed/35129074
http://dx.doi.org/10.1080/21505594.2022.2032928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824216/
https://www.ncbi.nlm.nih.gov/pubmed/35129074
http://dx.doi.org/10.1080/21505594.2022.2032928

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