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Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status

Both SARS-CoV-2 infections and COVID-19 vaccines elicit memory T cell responses. Here, we report the development of 2 pools of experimentally defined SARS-CoV-2 T cell epitopes that, in combination with spike, were used to discriminate 4 groups of subjects with different SARS-CoV-2 infection and COV...

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Detalles Bibliográficos
Autores principales: Yu, Esther Dawen, Wang, Eric, Garrigan, Emily, Goodwin, Benjamin, Sutherland, Aaron, Tarke, Alison, Chang, James, Gálvez, Rosa Isela, Mateus, Jose, Ramirez, Sydney I., Rawlings, Stephen A., Smith, Davey M., Filaci, Gilberto, Frazier, April, Weiskopf, Daniela, Dan, Jennifer M., Crotty, Shane, Grifoni, Alba, Sette, Alessandro, da Silva Antunes, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824221/
https://www.ncbi.nlm.nih.gov/pubmed/35172129
http://dx.doi.org/10.1016/j.chom.2022.02.003