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Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity

Although the exact pathogenesis of idiopathic pulmonary fibrosis (IPF) is still unknown, the transdifferentiation of fibroblasts into myofibroblasts and the production of extracellular matrix components such as collagen, triggered by alveolar epithelial cell injury, are important mechanisms of IPF d...

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Detalles Bibliográficos
Autores principales: Tanaka, Ken-ichiro, Shimoda, Mikako, Sugizaki, Toshifumi, Ikeda, Maki, Takafuji, Ayaka, Kawahara, Masahiro, Yamakawa, Naoki, Mizushima, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824291/
https://www.ncbi.nlm.nih.gov/pubmed/35136056
http://dx.doi.org/10.1038/s41420-022-00851-7