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Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity
Although the exact pathogenesis of idiopathic pulmonary fibrosis (IPF) is still unknown, the transdifferentiation of fibroblasts into myofibroblasts and the production of extracellular matrix components such as collagen, triggered by alveolar epithelial cell injury, are important mechanisms of IPF d...
Autores principales: | Tanaka, Ken-ichiro, Shimoda, Mikako, Sugizaki, Toshifumi, Ikeda, Maki, Takafuji, Ayaka, Kawahara, Masahiro, Yamakawa, Naoki, Mizushima, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824291/ https://www.ncbi.nlm.nih.gov/pubmed/35136056 http://dx.doi.org/10.1038/s41420-022-00851-7 |
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