Cargando…

Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing

Chronic inflammation is often associated with the development of tissue fibrosis, but how mesenchymal cell responses dictate pathological fibrosis versus resolution and healing remains unclear. Defining stromal heterogeneity and identifying molecular circuits driving extracellular matrix deposition...

Descripción completa

Detalles Bibliográficos
Autores principales: Jasso, Guadalupe J., Jaiswal, Alok, Varma, Mukund, Laszewski, Tyler, Grauel, Angelo, Omar, Abdifatah, Silva, Nilsa, Dranoff, Glenn, Porter, Jeffrey A., Mansfield, Keith, Cremasco, Viviana, Regev, Aviv, Xavier, Ramnik J., Graham, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824371/
https://www.ncbi.nlm.nih.gov/pubmed/35085231
http://dx.doi.org/10.1371/journal.pbio.3001532