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Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing
Chronic inflammation is often associated with the development of tissue fibrosis, but how mesenchymal cell responses dictate pathological fibrosis versus resolution and healing remains unclear. Defining stromal heterogeneity and identifying molecular circuits driving extracellular matrix deposition...
Autores principales: | Jasso, Guadalupe J., Jaiswal, Alok, Varma, Mukund, Laszewski, Tyler, Grauel, Angelo, Omar, Abdifatah, Silva, Nilsa, Dranoff, Glenn, Porter, Jeffrey A., Mansfield, Keith, Cremasco, Viviana, Regev, Aviv, Xavier, Ramnik J., Graham, Daniel B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824371/ https://www.ncbi.nlm.nih.gov/pubmed/35085231 http://dx.doi.org/10.1371/journal.pbio.3001532 |
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