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Danger-associated molecular pattern molecules and the receptor for advanced glycation end products enhance ANCA-induced responses

OBJECTIVES: The pro-inflammatory activities of the calgranulins and HMGB1 can be counteracted by sRAGE, the soluble form of their shared receptor. To understand the role of these molecules in AAV and their potential as therapeutic targets we have studied (i) the relationship between these DAMPS and...

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Detalles Bibliográficos
Autores principales: Page, Theresa H, Chiappo, Derick, Brunini, Francesca, Garnica, Josep, Blackburn, Jack, Dudhiya, Fayaz, Prendecki, Maria, McAdoo, Stephen P, Pusey, Charles D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824420/
https://www.ncbi.nlm.nih.gov/pubmed/33974049
http://dx.doi.org/10.1093/rheumatology/keab413