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Advances in the Design of (Nano)Formulations for Delivery of Antisense Oligonucleotides and Small Interfering RNA: Focus on the Central Nervous System

[Image: see text] RNA-based therapeutics have emerged as one of the most powerful therapeutic options used for the modulation of gene/protein expression and gene editing with the potential to treat neurodegenerative diseases. However, the delivery of nucleic acids to the central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Mendonça, Monique C. P., Kont, Ayse, Aburto, Maria Rodriguez, Cryan, John F., O’Driscoll, Caitriona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824433/
https://www.ncbi.nlm.nih.gov/pubmed/33734715
http://dx.doi.org/10.1021/acs.molpharmaceut.0c01238