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Intrinsic mechanisms in the gating of resurgent Na(+) currents

The resurgent component of the voltage-gated sodium current (I(NaR)) is a depolarizing conductance, revealed on membrane hyperpolarizations following brief depolarizing voltage steps, which has been shown to contribute to regulating the firing properties of numerous neuronal cell types throughout th...

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Detalles Bibliográficos
Autores principales: Ransdell, Joseph L, Moreno, Jonathan D, Bhagavan, Druv, Silva, Jonathan R, Nerbonne, Jeanne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824471/
https://www.ncbi.nlm.nih.gov/pubmed/35076394
http://dx.doi.org/10.7554/eLife.70173