Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

DNA damage response mechanisms have meiotic roles that ensure successful gamete formation. While completion of meiotic double-strand break (DSB) repair requires the canonical RAD9A-RAD1-HUS1 (9A-1-1) complex, mammalian meiocytes also express RAD9A and HUS1 paralogs, RAD9B and HUS1B, predicted to for...

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Detalles Bibliográficos
Autores principales: Pereira, Catalina, Arroyo-Martinez, Gerardo A, Guo, Matthew Z, Downey, Michael S, Kelly, Emma R, Grive, Kathryn J, Mahadevaiah, Shantha K, Sims, Jennie R, Faca, Vitor M, Tsai, Charlton, Schiltz, Carl J, Wit, Niek, Jacobs, Heinz, Clark, Nathan L, Freire, Raimundo, Turner, James, Lyndaker, Amy M, Brieno-Enriquez, Miguel A, Cohen, Paula E, Smolka, Marcus B, Weiss, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824475/
https://www.ncbi.nlm.nih.gov/pubmed/35133274
http://dx.doi.org/10.7554/eLife.68677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824475/
https://www.ncbi.nlm.nih.gov/pubmed/35133274
http://dx.doi.org/10.7554/eLife.68677

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