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Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity

GABAergic synaptic inhibition controls neuronal firing, excitability, and synaptic plasticity to regulate neuronal circuits. Following an acute excitotoxic insult, inhibitory synapses are eliminated, reducing synaptic inhibition, elevating circuit excitability, and contributing to the pathophysiolog...

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Detalles Bibliográficos
Autores principales: Garcia, Joshua D., Gookin, Sara E., Crosby, Kevin C., Schwartz, Samantha L., Tiemeier, Erika, Kennedy, Matthew J., Dell’Acqua, Mark L., Herson, Paco S., Quillinan, Nidia, Smith, Katharine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824488/
https://www.ncbi.nlm.nih.gov/pubmed/34936876
http://dx.doi.org/10.1016/j.celrep.2021.110142