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Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity
GABAergic synaptic inhibition controls neuronal firing, excitability, and synaptic plasticity to regulate neuronal circuits. Following an acute excitotoxic insult, inhibitory synapses are eliminated, reducing synaptic inhibition, elevating circuit excitability, and contributing to the pathophysiolog...
Autores principales: | Garcia, Joshua D., Gookin, Sara E., Crosby, Kevin C., Schwartz, Samantha L., Tiemeier, Erika, Kennedy, Matthew J., Dell’Acqua, Mark L., Herson, Paco S., Quillinan, Nidia, Smith, Katharine R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824488/ https://www.ncbi.nlm.nih.gov/pubmed/34936876 http://dx.doi.org/10.1016/j.celrep.2021.110142 |
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